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Eslicarbazepine Acetate

CAS No. 236395-14-5

Eslicarbazepine Acetate ( BIA 2-093 )

产品货号. M13678 CAS No. 236395-14-5

Eslicarbazepine acetate (BIA 2-093) 是一种抗癫痫活性分子,也是 β-内分泌酶 (β-Secretase) 和电压门控钠离子通道 (sodium channel) 的双抑制剂。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥259 有现货
10MG ¥373 有现货
25MG ¥680 有现货
50MG ¥1021 有现货
100MG ¥1401 有现货
200MG ¥2284 有现货
500MG ¥3345 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Eslicarbazepine Acetate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Eslicarbazepine acetate (BIA 2-093) 是一种抗癫痫活性分子,也是 β-内分泌酶 (β-Secretase) 和电压门控钠离子通道 (sodium channel) 的双抑制剂。
  • 产品描述
    Eslicarbazepine acetate is an antiepileptic drug. (In Vivo):Eslicarbazepine acetate is an antiepileptic drug. It is a prodrug which is activated to eslicarbazepine (S-licarbazepine), an active metabolite of oxcarbazepine. Eslicarbazepine acetate is a prodrug for (S)-(+)-licarbazepine, the major active metabolite of oxcarbazepine. Its mechanism of action is therefore identical to that of oxcarbazepine. Eslicarbazepine acetate may not produce as high peak levels of (S)-(+)-licarbazepine immediately after dosing as does oxcarbazepine which could theoretically improve tolerability.
  • 体外实验
    ——
  • 体内实验
    Eslicarbazepine acetate is an antiepileptic drug. It is a prodrug which is activated to eslicarbazepine (S-licarbazepine), an active metabolite of oxcarbazepine. Eslicarbazepine acetate is a prodrug for (S)-(+)-licarbazepine, the major active metabolite of oxcarbazepine. Its mechanism of action is therefore identical to that of oxcarbazepine. Eslicarbazepine acetate may not produce as high peak levels of (S)-(+)-licarbazepine immediately after dosing as does oxcarbazepine which could theoretically improve tolerability.
  • 同义词
    BIA 2-093
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Neurological Disease
  • 适应症
    ——

化学信息

  • CAS Number
    236395-14-5
  • 分子量
    296.324
  • 分子式
    C17H16N2O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 59 mg/mL (199.1 mM)/Ethanol: 11 mg/mL (37.12 mM)
  • SMILES
    O=C(N1C2=CC=CC=C2C[C@H](OC(C)=O)C3=CC=CC=C31)N
  • 化学全称
    (S)-10-Acetoxy- 10,11-dihydro- 5H-dibenz[b,f]azepine- 5-carboxamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Sierra-Paredes G, et al. BMC Neurosci. 2014, 15:134.
产品手册
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